Results 141 to 150 of about 2,977,823 (259)

Pediatric Rotavirus A Infection Among 337,019 Participants Within Asia: A Pan-Asian Systematic Review and Meta-Analysis

Journal of Tropical Medicine
Ali A. Rabaan, Bello E. Kizito, Abdulsalam Alawfi, Amer Alshengeti, Amal H. Alfaraj, Wadha A. Alfouzan, Haya Altawalah, Dalal Meshal Bashah, Alya Aali Almatrafi, Amal Abdulqadir Mujahed, Bandar Alwan Albaradi, Mohammed Garout, Heba A. Alsaffar, Mona A. Al-Zaher, Noor M. Al Sheef, Esraa Z. Al-Nass, Leia Kamal Mohammed AlKhathlan, Hayam A. Alrasheed, Nawal A. AlKaabi, Zainab H. Almansour, Huseyin Tombuloglu   +20 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

From career calling to proactivity in healthcare professionals: the roles of responsibility, mission commitment, and responsible leadership. [PDF]

Front Psychol
Chen J, Ren J.
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Workplace psychological violence among intern nursing students and its relationship with professional commitment: the moderating role of gender. [PDF]

Front Public Health
Zhong Y, Li Y, Yang H, Sun C, Li M, Zhao J.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Marriage: Commitment or Experiment? [PDF]

, 1996
Burke, Cormac
core   +1 more source

Impact of coping on resilience among nurse practitioners in Taiwan. [PDF]

J Am Assoc Nurse Pract
Wei CW, Kuo HH, Tung HH.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The impact of organizational commitment on the professional development of primary and secondary school physical education teachers: a moderated mediation model. [PDF]

Front Sports Act Living
Hu L, Zhao Y, Hao W, Zhang F.
europepmc   +1 more source