Results 131 to 140 of about 761,632 (319)

La sociologie au Maroc : retour réflexif et engagé d’un praticien

open access: yesSociologies, 2015
This paper tries to supply marks as regards the state of the Moroccan sociology in a reflexive and committed approach. Three main plans are investigated: 1) the question of the commitment, in its epistemological and historic dimensions; 2) the ...
Abdelmalek Ouard
doaj  

Bidding to Commit.

open access: yesEvolutionary psychology : an international journal of evolutionary approaches to psychology and behavior, 2017
Economists and biologists have both theorized that individuals can benefit from committing to courses of action because it forces others to concede a greater share of any surpluses, but little experimental work has tested the actual benefits of such a strategy and people's willingness to so "tie their hands." Participants played a Battle-of-the-Sexes ...
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Trapdoor commitment schemes and their applications

open access: yes, 2001
Informally, commitment schemes can be described by lockable steely boxes. In the commitment phase, the sender puts a message into the box, locks the box and hands it over to the receiver.
Fischlin, Marc
core  

Sur le concept d’engagement

open access: yesSociologies, 2006
The term "commitment" is experiencing a growing success in sociological debates. In this article, the author examines the uses of the concept of commitment in order to understand the reasons for its growing popularity.
Howard S. Becker
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The determinants and outcomes of user commitment to mandatory information system change

open access: yes, 2011
Includes abstract.Includes bibliographical references (p. 248-287).Winning the commitment and support of employees for organisational transformation is a major objective of the leaders of organisational change.
Schneider, Matthias H M
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Identity cards and political commitment: a study in the formation, operationalisation and measurement of a concept

open access: yes, 2012
This thesis presents a new definition of the concept of political commitment. It shows how the concept can be operationalised for empirical research in parliamentary and executive settings, and reports findings from a study to measure the commitment of ...
Denny, R
core  

Home - About - Disclaimer - Privacy