Results 121 to 130 of about 2,977,823 (259)

ABSENTEÍSMO E COMPROMETIMENTO: NOVAS REFLEXÕES A PARTIR DE UM ESTUDO DE CASO ANALISADO SOB A ÓTICA DA PSICODINÂMICA DO TRABALHO

open access: yesAção Ergonômica, 2003
This paper presents the results of a case study carried out in a large-scale Brazilian company, of the services sector, and the objective was to comprehend the questions of absenteeism and commitment at work.
Maria Irene Stocco Betiol   +1 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

La sociologie au Maroc : retour réflexif et engagé d’un praticien

open access: yesSociologies, 2015
This paper tries to supply marks as regards the state of the Moroccan sociology in a reflexive and committed approach. Three main plans are investigated: 1) the question of the commitment, in its epistemological and historic dimensions; 2) the ...
Abdelmalek Ouard
doaj  

Taxation without Commitment [PDF]

open access: yes
This paper considers a Ramsey model of linear capital and labor income taxation in which a benevolent government cannot commit ex-ante to a sequence of taxes for the future. In this setup, if the government is allowed to borrow and lend to the consumers,
Reis, Catarina
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Sur le concept d’engagement

open access: yesSociologies, 2006
The term "commitment" is experiencing a growing success in sociological debates. In this article, the author examines the uses of the concept of commitment in order to understand the reasons for its growing popularity.
Howard S. Becker
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

LEADERSHIP STYLE AND ORGANIZATIONAL COMMITMENT: TEST OF A THEORY IN TURKISH BANKING SECTOR [PDF]

open access: yes
The aim of this study is to explore the effects of leadership on organizational commitment in general and to question the role played by transactional and transformational leadership in improving organizational commitment of branch employees.
IBRAHIM SANI MERT   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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