Results 101 to 110 of about 761,632 (319)

A commitment renewed

open access: yesIndian Journal of Pharmacology, 2010
With this issue, a new editorial team takes over the reins of Indian Journal of Pharmacology. Although the names (and designations) may have changed (a little), the dedication remains the same. The new Chief Editor and the editorial team feel honored in doing a job that has been done so admirably in the past by a number of stalwarts.
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Work-family Conflict and Organisational Commitment in Malaysia

open access: yes, 2014
This study examined the relationship between work-family conflict (WFC) and organisational commitment, and considered gender and number of dependents as moderators.
Siu, Yen Pin
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Trust and Commitment in Professional Service Marketing Relationships in Business-to-Business Markets [PDF]

open access: yes
This paper examines two very important concepts in marketing relationships – trust and commitment – whereby commitment is regarded as consisting of three components: affective, calculative and normative. The context of this study is professional services
Barbara Cater
core  

Identification-commitment inventory (ICI model): confirmatory factor analysis and construct validity

open access: yes, 2010
Organizational commitment, Organizational identification, Confirmatory factor analysis, Structural equation modeling, Elliptical least square solution,
Yepes i Baldó, Montserrat   +9 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Limits of Limited Commitment

open access: yes
We study limited strategic leadership. A collection of subsets covering the leader's action space determines her commitment opportunities. We characterize the outcomes resulting from all possible commitment structures of this kind.
Bizzotto, Jacopo   +2 more
core  

Home - About - Disclaimer - Privacy