Results 111 to 120 of about 392,256 (269)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Sosyal Ekonomik Araştırmalar Dergisi, 2007 Bu araştırmanın amacı;çalışanların iş tatminleri ve örgütsel bağlılıkları arasındaki ilişkinin incelenmesidir.Araştırma teorik bir çerçeve ile sunulduktan sonra konuyu desteklemek amacıyla ampirik bir araştırma yapılmıştır.Ampirik araştırma ilaç ...
Hatice Necla Keleş
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Association between distributed leadership and teachers' organizational commitment: Evidence from public and private schools in the United Arab Emirates. [PDF]
PLoS OneIbrahim A, Alshehhi S, Tsingilis N.
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Beyond retention: an ecological analysis of teacher commitment and agency in rural China. [PDF]
Front PsycholWei J, Wang S, Fan S.
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Network analysis of psychological capital: mapping interconnected dynamics in teacher wellbeing and professional commitment. [PDF]
Front PsycholYanran Z, Ishak Z, Bicheng D.
europepmc +1 more source