Results 31 to 40 of about 437 (212)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Noise Suppression of Nitrogen-Vacancy Magnetometer in Lock-In Detection Method by Using Common Mode Rejection

Micromachines, 2023
Nitrogen-vacancy (NV) centers in diamonds are promising solid-state magnetic sensors with potential applications in power systems, geomagnetic navigation, and diamond NV color center current transformers, in which both high bandwidth and high magnetic ...
Yang Li, Doudou Zheng, Zhenhua Liu, Hui Wang, Yankang Liu, Chenyu Hou, Hao Guo, Zhonghao Li, Yashuhiro Sugawara, Jun Tang, Zongmin Ma, Jun Liu   +11 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A strategy of neutral-point potential balance control and common-mode voltage suppressio

Gong-kuang zidonghua, 2014
For problems that there are common-mode voltage, over voltage and neutral-point potential imbalance simultaneously in power supply of inverter to motor through long cable, generation mechanisms of common-mode voltage and over voltage were analyzed as ...
WANG Kezhi, ZHAO Wenhan, WANG Tao, YANG Gang, CHENG Guodong, GENG Yiwen   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Compact and Wideband Differentially Fed Dual-Polarized Antenna With High Common-Mode Suppression

IEEE Access, 2019
A compact and wideband differentially fed dual-polarized antenna with high common-mode suppression is investigated in this paper. A square patch with crossed-slot consisting of four slant funnel-shaped slots is used as the radiator, generating slant ...
Zhao Zhou, Zhaohui Wei, Zhaoyang Tang, Yingzeng Yin, Jian Ren   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A Miniaturized Balanced-to-Unbalanced In-Phase Filtering Power Divider With Wide Upper Stopband and Wideband Common-Mode Suppression

IEEE Access, 2021
A miniaturized balanced-to-unbalanced in-phase filtering power divider with wide upper stopband and wideband common-mode suppression is proposed. The in-phase feature is realized by the coupled/non-coupled lines.
Zhongbao Wang, Zihui Zhu, Ye Fu, Peng Han, Hongmei Liu, Shaojun Fang   +5 more
doaj   +1 more source