Results 51 to 60 of about 437 (212)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

An Enabling Multi-Operation Branch-Line Coupler

open access: yesIEEE Access, 2019
In this paper, an enabling multi-operation branch-line coupler is proposed initially. The proposed design is configured by ±90° and 180° transmission lines, and the main advantage is that the proposed design can be applied in three ...
Jin Shi   +4 more
doaj   +1 more source

Dual-Band Differential Bandpass Filters Using Quadruple-Mode Stubs-Loaded Ring Resonator With Intrinsic Common-Mode Suppression for 5G

open access: yesIEEE Access, 2020
A novel quadruple-mode stubs-loaded ring resonator (SLRR) is presented in this letter, which can achieve compact dual-band differential bandpass filters (BPFs) with intrinsic common-mode suppression.
Xuehui Guan, Bo Zhao, Baoping Ren
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Balanced Linear-Phase Bandpass Filter Equalized with Negative Group Delay Circuit [PDF]

open access: yesRadioengineering
A novel balanced linear-phase bandpass filter is proposed to achieve differential-mode linear-phase filtering and common-mode suppression characteristics.
Z. C. Wang   +4 more
doaj  

Design of compact balanced ultra‐wideband bandpass filter with half mode dumbbell DGS

open access: yesElectronics Letters, 2016
A new compact balanced ultra‐wideband (UWB) bandpass filter using half mode dumbbell defected ground structure (DGS) is presented. To realise the UWB response, the ‘T’ shape multiple‐mode resonator with short‐ended stub is employed.
Jiayuan Lu, Jianpeng Wang, Hui Gu
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Multilayered Balanced Dual-Band Bandpass Filter Based on Magnetically Coupled Open-Loop Resonators with Intrinsic Common-Mode Rejection

open access: yesApplied Sciences, 2020
A new dual-band balanced bandpass filter based on magnetically coupled open-loop resonators in multilayer technology is proposed in this paper. The lower differential passband, centered at the Global Positioning System (GPS) L1 frequency, 1.575 GHz, was ...
Jose L. Medran del Rio   +5 more
doaj   +1 more source

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