Results 81 to 90 of about 153,833 (299)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Wideband balanced combline filter with extended common-mode suppression
Electronics Letters, 2011 A wideband differential-mode combline filter with a tapped-line input is presented. High suppression of the common-mode and a small size are two important features of the proposed filter. The filter combines two conventional combline filters connected together through discrete capacitors.
Taslimi, A., Mouthaan, K.
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Common-mode phase noise suppression with an open-loop differential phasemeter
Optics ExpressWe present direct differential phase recovery-an open-loop phasemeter topology for differential optical interferometric measurements. The technique aims to remove common mode signal dynamics prior to phase-tracking, which reduces the dynamic range requirements of the phasemeter tracking optical phase differences.
Anneshwa Dey +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The effective capacitance of the common mode port serves as a critical metric for assessing the common mode noise suppression capability of transformers in power converters.
Wei Chen, Yipeng Kong
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Shaft Voltage Suppression of Double-fed Generator for High Power Wind Turbine
Kongzhi Yu Xinxi Jishu, 2013 The mechanism and adverse effects of shaft voltage in double-fed generator generated by inverter is analyzed. As shaft voltage is part of common-mode voltage, a new LCL-filter of converter for suppression of common-mode voltage is proposed through ...
CAO Guorong +5 more
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