Results 51 to 60 of about 12,111,967 (266)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Best proximity point theorems for proximal cyclic contractions

, 2017
The purpose of this article is to compute a global minimizer of the function x to d(x, Tx) , where T is a proximal cyclic contraction in the framework of a best proximally complete space, thereby ensuring the existence of an optimal approximate solution,
Vetro, C., S. Sadiq Basha, N. Shahzad, C. Vetro, Basha, S. Sadiq, Shahzad, N.   +5 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Best proximity point results for modified α-proximal C-contraction mappings

, 2014
First we introduce new concepts of contraction mappings, then we establish certain best proximity point theorems for such kind of mappings in metric spaces.
Salimi, P, Kumam, P, VETRO, Calogero
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A simulation function approach for optimization by approximate solutions with an application to fractional differential equation

Nonlinear Analysis
In this work, we study the existence and uniqueness of a common best proximity point for a pair of nonself functions that are not necessarily continuous using the simulation function.
Parvaneh Lo'lo', Maryam Shams, Stojan Radenović   +2 more
doaj   +1 more source

Parallelism of the Occlusal Plane with the Ala-tragus Line in Various Posterior References in Dentate Patients

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Occlusal plane in edentulous patients is lost and needs to be reconstructed. The most common method for reconstructing occlusal plane is to make it parallel to the ala-tragus line.
Negareh Salehabadi, Navid Pournasiri, Tahmineh Bamdadian, Kosar Dadgar, Hadi Mokhtarpour, Alireza Khalilian, Mohammad Ebrahimi Saravi   +6 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Biomedical research in france and brazil: an analysis of significant differences and ethical issues

Revista Brasileira em Promoção da Saúde, 2016
At first sight, Brazil and France seem pretty distant from one another, but on the map, they are not separated by the Atlantic Ocean, but by the Oyapock River, located between the state of Amapa and French Guiana (French overseas department), creating a ...
Hervé Moizan
doaj   +1 more source

Common Best Proximity Points in CR Metric Spaces

Iraqi Journal of Science
Throughout this paper, a new generalization of complex valued CR  -metric space is used. This definition was stated in published research as a previous work. In this paper, some new results on common best proximity points for non-self-mappings are obtained in these spaces. It is an extension of previous results proven in classical complex metric spaces.
Annam Nama Faraj, Salwa Salman Abed
openaire   +1 more source