Results 71 to 80 of about 14,032,665 (282)

Biomedical research in france and brazil: an analysis of significant differences and ethical issues

Revista Brasileira em Promoção da Saúde, 2016
At first sight, Brazil and France seem pretty distant from one another, but on the map, they are not separated by the Atlantic Ocean, but by the Oyapock River, located between the state of Amapa and French Guiana (French overseas department), creating a ...
Hervé Moizan
doaj   +1 more source

Best proximity point theorems for proximal cyclic contractions

, 2017
The purpose of this article is to compute a global minimizer of the function x to d(x, Tx) , where T is a proximal cyclic contraction in the framework of a best proximally complete space, thereby ensuring the existence of an optimal approximate solution,
Vetro, C., S. Sadiq Basha, N. Shahzad, C. Vetro, Basha, S. Sadiq, Shahzad, N.   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A Generalization for the Best Proximity Point of Geraghty-Contractions [PDF]

, 2013
KARAPINAR, ERDAL/0000-0002-6798-3254In this paper, we introduce the notion of Geraghty-contractions and consider the related best proximity point in the context of a metric space.
Sadarangani, Kishin, Bilgili, Nurcan, Karapinar, Erdal, Karapınar, Erdal   +3 more
core   +2 more sources

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Best Proximity Points of Relatively Jaggi Nonexpansive Mappings in Busemann Convex Spaces

Journal of Function Spaces
In this paper, we introduce cyclic (noncyclic) relatively Jaggi nonexpansive mappings on Busemann convex spaces and investigate the existence of their best proximity points (pairs).
M. Gabeleh, M. Hassanvand, H. R. Salimi Moghaddam   +2 more
doaj   +1 more source