Results 81 to 90 of about 366,599 (355)

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

open access: yesAdvanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang   +11 more
wiley   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu   +11 more
wiley   +1 more source

Manual and automated media and intima thickness measurements of the common carotid artery

open access: yesIEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2009
The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of the development of cardiovascular disease (CVD).
C. Loizou   +3 more
semanticscholar   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

open access: yesAdvanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li   +17 more
wiley   +1 more source

Dissection of the Common Carotid Artery [PDF]

open access: yesJournal of Diagnostic Medical Sonography, 2000
Dissection of the aorta is a common catastrophic event affecting the aorta. However, aortic dissections do not normally extend into the common carotid arteries. This case study discusses such an occurrence and the role of sonography in its detection and diagnosis.
openaire   +1 more source

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

open access: yesAdvanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li   +15 more
wiley   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

The Clinical Study on Bell's Palsy Patients with TCD Measurement

open access: yesJournal of Pharmacopuncture, 2003
Objective : This study was carried to make out the connection between cerebral artery blood flow velocity and ischemic theory that presumed the cause of Bell's palsy. Method : We measured cerebral artery blood flow velocity each external carotid artery,
Lee Hyun, Lee Byung-ryul, Ann Taek-won
doaj   +1 more source

A systematic study of the brain base arteries in the rabbit (Oryctolagus cuniculus)

open access: yesPesquisa Veterinária Brasileira, 2013
The brains of 30 New Zealand rabbits (Oryctolagus cuniculus) were injected with red stained latex. The arteries of the ventral surface of the brain were systematized on the right (R) and on the left (L) side with the respective percentage of appearance ...
Fernanda de Souza, Rui Campos
doaj   +1 more source

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