Results 61 to 70 of about 2,386,509 (293)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Scientia Pharmaceutica, 2017 Plants have been used since antiquity to treat and prevent diseases. Plantain (Plantago lanceolata L.) is traditionally used for the treatment of the common cold and associated symptoms such as cough. This study was designed to evaluate the oral toxicity
Kenza Mansoor +5 more
doaj +1 more source
"Weak Quantum Chaos" and its resistor network modeling
, 2011 Weakly chaotic or weakly interacting systems have a wide regime where the common random matrix theory modeling does not apply. As an example we consider cold atoms in a nearly integrable optical billiard with displaceable wall ("piston").
Cohen, Doron +2 more
core +1 more source
Asymmetric dark matter: residual annihilations and self-interactions [PDF]
, 2017 Dark matter (DM) coupled to light mediators has been invoked to resolve the putative discrepancies between collisionless cold DM and galactic structure observations. However, $\gamma$-ray searches and the CMB strongly constrain such scenarios.
Baldes, Iason +5 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Behavioral Sciences, 2012 Previous research has shown that both experimentally induced upper respiratory tract illnesses (URTIs) and naturally occurring URTIs influence mood and performance.
Andrew P. Smith
doaj +1 more source
Tropical Medicine and Infectious Disease, 2022 The COVID-19 pandemic circumstances have varied the pathogens related to acute respiratory infections (ARI), and most specialists have ignored them due to SARS-CoV-2’s similar symptomatology.
Juan Carlos Gómez de la Torre Pretell +8 more
doaj +1 more source
Automatic effects of illness schema activation on behavioral manifestations of illness. [PDF]
, 2016 Objective: Relatively little research has directly evaluated the schematic nature of illness representations proposed by the common sense model of illness. Four studies tested the hypothesis that illness schema activation leads directly and automatically
Henderson, Caroline J, Orbell, Sheina
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source