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Common colds in Antarctica [PDF]
Epidemiology and Infection, 1973 Recent studies have established that the occurrence of common cold epidemics amongst men in Antarctica shows a pattern similar to that seen in other isolated communities such as Tristan da Cunha (Cameron & Moore, 1968; Shibli, Gooch, Lewis & Tyrrell, 1971). Colds occur during relief periods when ships and aircraft call, and disappear during the
openaire +3 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
, 2020 WATER SUPPLY IN COLD REGIONS Amos J. Al ter January 1969 GB 2401 ,U58m lll-C5a 1969 LD U.S. ARMY MA T ERIE L COMMAND TERRE S TRIA L SCIENCES CENTER REGIONS RESEARCH A ENGINEERING LABORATORY HANOVER, NEW HAMPSHIRE T H I S D O C U M E N T H A S B E E N A P
Cold Regions Research and Engineering Laboratory (U.S.)
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
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, 2014 Proponents of evidence-based medicine (EBM) emphasize that conclusions about medical interventions should be based on controlled trials with clinically relevant outcomes, so that the greatest weight should be given to the systematic reviews of the trials.
Common Cold, Harri Hemilä
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FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
, 2021 Upper respiratory tract infection (URI) represents the most common acute illness evaluated in the outpatient setting. URIs range from the common cold—typically a mild, self-limited, catarrhal syndrome of the nasopharynx—to life-threatening illnesses such
Nihat Susaman +5 more
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