Results 91 to 100 of about 6,106,849 (291)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Common Cold Questionnaire

, 2013
Common Cold ...
Peter G. Gibson (88654), Heather Powell (88648), Joanne Smart (88649), Michael J. Hensley (88653), Terry Grissell (88651), Lisa G. Wood (88650), Darren R. Shafren (88652)   +6 more
core   +1 more source

The Cold Peace: Russo-Western Relations as a Mimetic Cold War [PDF]

, 2013
In 1989–1991 the geo-ideological contestation between two blocs was swept away, together with the ideology of civil war and its concomitant Cold War played out on the larger stage.
Sakwa, Richard, Richard Sakwa
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

“Fever means antibiotic”, the Omani public’s attitudes to the use of antibiotics for treating the common cold [PDF]

, 2018
Background: Antimicrobial resistance is a worldwide concern to reserve the effectiveness of antibiotics in therapy. The irrational use of antibiotics is one of the factors contributing to antimicrobial resistance.
Boyd, Matthew J., Al Juma, Muna A., Anderson, Claire   +2 more
core  

Treatment of the common cold

BMJ, 1998
The common cold is the most frequent illness managed in general practice. Despite a long search for a cure only potential treatments for the symptoms have been established. Colds afflict most adults two to four times a year and children four to eight times a year, and the resulting hours of absenteeism from work or school have enormous economic ...
openaire   +3 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Sex-Specific Associations between Prenatal Exposure to Di(2-ethylhexyl) Phthalate, Epigenetic Age Acceleration, and Susceptibility to Early Childhood Upper Respiratory Infections

Epigenomes
Di(2-ethylhexyl) phthalate (DEHP) is a common plasticizer that can affect immune system development and susceptibility to infection. Aging processes (measured as epigenetic age acceleration (EAA)) may mediate the immune-related effects of prenatal ...
Sarah M. Merrill, Nicole Letourneau, Gerald F. Giesbrecht, Karlie Edwards, Julia L. MacIsaac, Jonathan W. Martin, Amy M. MacDonald, David W. Kinniburgh, Michael S. Kobor, Deborah Dewey, Gillian England-Mason, The APrON Study Team   +11 more
doaj   +1 more source

Scientific Opinion on the substantiation of a health claim related to ProteQuine® and bovine lactoferrin and increasing suppressed concentrations of secretory IgA and reducing the risk of common cold with sore throat pursuant to Article 14 of Regulation (EC) No 1924/2006

EFSA Journal, 2011
Following an application from SVUS Pharma a.s. submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of the Czech Republic, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source