Results 161 to 170 of about 99,860 (311)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

An Intergenerational Common Pool Resource Experiment

intergenerational common pool resources;growth and altruism;free-riding ...
Irlenbusch, B., Sadrieh, A., Fischer, M.E.   +2 more
core  

An insect that cooperates like bacteria. [PDF]

Proc Natl Acad Sci U S A
West SA, Griffin AS.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The Austrian School on Happiness and Relational Goods [PDF]

Austrian economists do not directly face the problem of the relationships between economics and happiness. They even rather rarely use the word happiness and do not bother to define the philosophical meaning of it referring to Aristotle or to the ...
Antonio Magliulo
core  

Financing Common Goods for Health: Fundamental for Health, the Foundation for UHC

Health Systems & Reform, 2019
Agnès Soucat
doaj   +1 more source

Accounting for uncertainty and bias in archaeological and historical evidence on wealth inequality. [PDF]

Proc Natl Acad Sci U S A
Fochesato M, Bowles S.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Dynamic Analysis of the Evolution of Conventions in a Public Goods Experiment with Intergenerational Advice [PDF]

In this paper we analyse contributions to a public good within an inter-generational framework where at the end of each session one generation of subjects leave advice for the succeeding generation via free form messages.
Ananish Chaudhuri, Sara Graziano, Pushkar Maitra   +2 more
core  

Harmony, Basic Goods, and the Biopsychosocial-Spiritual Model: A Philosophical Anthropology That Can Lead to Better Healthcare. [PDF]

Linacre Q
Lisanti CJ, Shonnard MJ.
europepmc   +1 more source