Results 51 to 60 of about 99,860 (311)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Les bénéfices sociaux et environnementaux des systèmes agricoles : une analyse ostromienne de trois terrains d’étude en France

open access: yesDéveloppement Durable et Territoires, 2020
This article uses the Ostrom’s notion of socio-ecological system in order to characterize agricultural practices generating social and environmental benefits and to identify factors that ease or limit their implementation.
Marielle Berriet-Solliec   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Une introduction aux communs de la connaissance

open access: yesTic & Société, 2018
We propose an introduction to the knowledge commons based on an attempt to define the commons themselves, and then evaluate how they are related to the intangible fields of knowledge and the digital. It seems difficult to settle on a canonical definition
Hervé LE CROSNIER
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Dynamic Performance Management: An approach for managing the common goods [PDF]

open access: yes, 2019
Public organizations need innovative approaches for managing common goods and to explain the dynamics linking the (re)generation of common goods and organizational performance.
Enrico Sorano   +3 more
core   +1 more source

Il ruolo delle pratiche di riuso e condivisione degli spazi aperti nei processi di commoning urbano

open access: yesRi-vista: Ricerche per la Progettazione del Paesaggio, 2016
The role of the practices of reuse and sharing of open spaces in the processes of urban commoning. This essay examines the perspectives that the practices of reuse and sharing of open spaces, which over time have lost their original function (the so ...
Giuseppe Caridi
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Role of Rivalry. Public Goods versus Common-Pool Resources [PDF]

open access: yes
Despite a large theoretical and empirical literature on public goods and common-pool resources, a systematic comparison of these two types of social dilemmas is lacking. In fact, there is considerable confusion about these two types of dilemma situations.
Jose Apesteguia, Frank P. Maier-Rigaud
core  

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