Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar +7 more
wiley +1 more source
Vegan Sesame Milk Ice Cream With Probiotic Bacteria (<i>Lactobacillus casei</i>) and Hibiscus (<i>Hibiscus sabdariffa</i>) Calyces Extract: Formulation, Characterization, and Stability. [PDF]
Didar Z +2 more
europepmc +1 more source
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka +2 more
wiley +1 more source
Causes and consequences of bacterial local adaptation via MGEs in the plant microbiome. [PDF]
Porter S +3 more
europepmc +1 more source
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Improving Freeze-Thaw Stability of High-Moisture Extruded Plant-Based Meat: A Synergistic Strategy Combining Glucose Oxidase, Phytase and Tamarind Gum. [PDF]
Wang X, Zeng X, Li J.
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Polyethylene Microplastics Exert Dose-Dependent Effects on the Growth, Physiology, and Rhizosphere Microbiome of <i>Persicaria capitata</i>. [PDF]
Ma R +9 more
europepmc +1 more source
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph +11 more
wiley +1 more source
Secreted proteins from <i>Bacillus subtilis</i> K1 induce apple resistance against gray mold. [PDF]
Li P, Sun Y, Feng B, Wei L.
europepmc +1 more source

