Results 81 to 90 of about 141,769 (294)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Line current ripple reduction of two paralleled three‐phase two‐level converter using optimized common‐mode voltage injections

IET Power Electronics, 2021
This paper proposes a common‐mode voltage injection‐based pulse width modulation strategy to optimize the AC current ripple of parallel interleaved converters.
Shengfu Liu, Xiaoliang Jin, Wen Shi, Huan Yang, Rongxiang Zhao   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reduced Common Mode Voltage PWM Strategy With Optimized Switching Sequence for Three Phase Motor Drives

IEEE Access
This paper proposes a pulse width modulation (PWM) switching sequence strategy aimed at minimizing common-mode voltage (CMV) in three-phase motor drive systems.
Suji Seo, Sehwan Kim, Hyeon-Jae Shin, Cheewoo Lee, Jae Suk Lee   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Design of current sources for load common mode optimization

Journal of Electrical Bioimpedance, 2018
Bioimpedance measurement systems often use the Howland current sources to excite the biological material under study. Usually, difference or instrumentation amplifiers are used to measure the resulting voltage drop on this material.
Sirtoli Vinicius G, Morcelles Kaue F, Vincence Volney C   +2 more
doaj   +1 more source

A finite control set model predictive control method for matrix converter with zero common-mode voltage [PDF]

, 2018
In this paper a finite control set model predictive control method is presented that eliminates the common-mode voltage at the output of a matrix converter.
Dan, Hanbing, Pat Wheeler, Wang, Lina, Peng, Tao, Wheeler, Patrick, Sun, Yao, Qi Zhu, Yao Sun, Zhao, Yue, Lina Wang, Hanbing Dan, Yue Zhao, Zhu, Qi, Tao Peng   +13 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An Active Common-Mode Voltage Canceler for PWM Converters in Wind-Turbine Doubly-Fed Induction Generators

Energies, 2019
Wind energy integration in power grids is increasing day by day to reduce the use of fossil fuels, and consequently greenhouse gas emissions. Using the pulse-width modulated (PWM) power converters in wind turbine generators, specifically in doubly-fed ...
Amr. S. Zalhaf, Mazen Abdel-Salam, Mahmoud Ahmed   +2 more
doaj   +1 more source