Results 81 to 90 of about 137,530 (263)

Common-mode voltage suppression for traction drive systems based on carrier phase shift control

open access: yes机车电传动
To suppress the common mode voltage generated by the traction system due to inverter pulse-width modulation (PWM) and to reduce electrical corrosion of the bearings and electromagnetic compatibility (EMC) interference, this paper proposes a strategy for ...
ZHANG Ying   +5 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Simulation Research on Zero-vector PWM Common-mode Voltage Suppression for Clamped Five-level Converters

open access: yesKongzhi Yu Xinxi Jishu, 2018
Although more and more common-mode voltage suppression methods have been adopted for high power multi-level converter, the common-mode voltage has not been completely removed.
LI Yinling
doaj  

Stability Analysis of Bipolar LVDC Grid

open access: yesInternational Transactions on Electrical Engineering and Computer Science, 2022
The study and regulation of bipolar DC structures covered by asymmetrical action, the DC symmetric part approach is implemented. This approach is an expansion of the standard principle of symmetrical components in three phase AC-controlled networks.
T. Raghu, D. Rajesh Reddy
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Modelling and suppression of bearing voltage of wind turbine permanent magnet synchronous generators

open access: yesIET Electric Power Applications
The problem of bearing current is common in wind power generation system, which leads to the attenuation of generator life and great economic losses. Bearing voltage of a 5.5 MW wind‐turbine permanent magnet synchronous generator is studied.
Lei Jia   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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