Results 31 to 40 of about 162,460 (297)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

「人類共同遺產」原則與「共有資源」管理 ― 概念定位與制度要素之比較研究 The Principle of Common Heritage of Mankind and the Management of Common Pool Resources ― A Comparative Study on the Concepts and the Institutional Designs [PDF]

open access: yesKējì Fǎxué Pínglùn, 2010
Most of the environmental problems result from the over-exploitation and use of the so-called “common pool resources.” From the perspective of the global commons, these resources are characterised as either the “common heritage of mankind” or the “common
施文真 Wen-Chen Shih
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Commons Dilemma pada Pengelolaan Daerah Irigasi Kapilaler, Kabupaten Klaten

open access: yesJurnal Wilayah dan Lingkungan, 2015
Water resource is a part of common pool resources. In the management, common pool resources are faced with triggered conflicts between stakeholders because the resource characteristics are freely used by everyone, but its useful will be decreased.
Wahyu Indriastuti, Mohammad Muktiali
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

POST-SOCIALIST LABOR FORCE AS A COMMON-POOL RESOURCE [PDF]

open access: yesTrakia Journal of Sciences, 2019
The article is devoted to the challenges of the labour market in the post-socialist period. It discusses the issues related to the physical properties of the post-socialists labour force and the social and legal framework in which it operates.
Iv. Penov
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Household-level heterogeneity of water resources within common-pool resource systems

open access: yesEcology and Society, 2017
Prior work has demonstrated the ability of common property systems to sustain institutional arrangements governing natural resources over long periods of time.
Paul McCord   +4 more
doaj   +1 more source

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