Results 51 to 60 of about 313,173 (266)

Analyzing recurrent events when the history of previous episodes is unknown or not taken into account: proceed with caution

Gaceta Sanitaria, 2017
Objective: Researchers in public health are often interested in examining the effect of several exposures on the incidence of a recurrent event. The aim of the present study is to assess how well the common-baseline hazard models perform to estimate the ...
Albert Navarro, Georgina Casanovas, Sergio Alvarado, David Moriña   +3 more
doaj   +1 more source

Interindividual variation of progesterone elevation post LH rise: implications for natural cycle frozen embryo transfers in the individualized medicine era

Reproductive Biology and Endocrinology, 2023
Background The key to optimal timing of frozen embryo transfer (FET ) is to synchronize the embryo with the receptive phase of the endometrium. Secretory transformation of the endometrium is induced by progesterone.
Carol Coughlan, Baris Ata, Raquel Del Gallego, Barbara Lawrenz, Laura Melado, Suzan Samir, Human Fatemi   +6 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

On the statistical optimality of CO₂ atmospheric inversions assimilating CO₂ column retrievals [PDF]

Atmospheric Chemistry and Physics, 2015
The extending archive of the Greenhouse Gases Observing Satellite (GOSAT) measurements (now covering about 6 years) allows increasingly robust statistics to be computed, that document the performance of the corresponding retrievals of the column-average ...
F. Chevallier
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Signaling Without Common Prior: An Experiment [PDF]

The common prior assumption is pervasive in game-theoretic models with incomplete information. This paper investigates experimentally the importance of inducing a common prior in a two-person signaling game. For a specific probability distribution of the
Michalis Drouvelis, Wieland Muller, Alex Possajennikov   +2 more
core   +3 more sources

Sharing the Mask: TFHE Bootstrapping on Packed Messages

Transactions on Cryptographic Hardware and Embedded Systems
Fully Homomorphic Encryption (FHE) schemes typically experience significant data expansion during encryption, leading to increased computational costs and memory demands during homomorphic evaluations compared to their plaintext counterparts.
Loris Bergerat, Charlotte Bonte, Benjamin R. Curtis, Jean-Baptiste Orfila, Pascal Paillier, Samuel Tap   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Security Culture: Surveillance and Responsibilization in a Prisoner Reentry Organization

, 2020
As they have become increasingly common, prisoner reentry organizations have become a topic of interest to ethnographers, particularly those focused on race crime and justice. Reentry organizations are typically understood in terms of the social services
Prior, Francis B.
core   +1 more source