Results 101 to 110 of about 432,765 (298)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Between formality and informality: the role of partnerships to co-create cultural value of industrial heritage

Valori e Valutazioni
Analyzing the cultural value of industrial artefacts is particularly challenging due to lack of recognition as heritage assets and misconceptions related to previous uses and feeling of unwanted heritage.
Danny Casprini , Alessandra Oppio , Mario Calderini   +2 more
doaj   +1 more source

Media education and educational commons for youth civic engagement. A case study from the Horizon 2020 project SMOOTH. [PDF]

Front Sociol, 2022
Cappello G, Siino M.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

On Hydrangea peruviana, an endangered species from Ecuador, and Hydrangea oerstedii, very common in Costa Rica and Panama, and seven threatened Central and South American Hydrangeas, which have been confounded with these

, 2021
Marie‐Stéphanie Samain, Carolina Granados Mendoza, Esteban M. Martínez Salas   +2 more
openalex   +1 more source

Review Common Marketing Types and Describe Network Marketing in Kurdistan Region [PDF]

, 2022
Accounting Department, Faculty of Law, Political Science, and Management, Soran University, Soran, Erbil, Kurdistan, Iraq
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Joining with the Conversation: Research as a Sustainable Practice in the Sport Sciences. [PDF]

Sports Med Open, 2022
Woods CT, Araújo D, Davids K.
europepmc   +1 more source

#454\, Edmund Gerald Brown, interview w/ Canadian Broadcasting Corporation, regarding North American Common Market, 1981-02-12

, 2021
Unknown
openalex   +1 more source