Results 111 to 120 of about 3,872 (299)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Publicness and commoning: Pandemic intersections and collective visions at times of crisis. [PDF]
Georgiou M, Titley G.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Micro-Care in Motion: Commoning Kindness as Ethical Planning Practice
This presentation explores how everyday mobility depends not only on transport infrastructure, but also on small acts of care, kindness, and support that help people move, wait, and navigate vulnerability.
Wendy Tan, Enrica Papa
core +1 more source
Riverhood: political ecologies of socionature commoning and translocal struggles for water justice. [PDF]
Boelens R +28 more
europepmc +1 more source
Environmental archaeology has often relied on common-pool resource models to interpret past human-environment relationships, yet these frameworks overlook Indigenous ontologies grounded in kinship with land, water, and more-than human beings.
Jessica A. Jenkins +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Rethinking GLAMs as commons: a conceptual framework. [PDF]
Avdikos V +3 more
europepmc +1 more source

