Results 71 to 80 of about 482,047 (285)

Glaucoma blindness–A rapidly emerging non-communicable ocular disease in India: Addressing the issue with advocacy

Journal of Family Medicine and Primary Care, 2020
Glaucoma, a leading cause of irreversible blindness, can be prevented or stabilized the progression if identified early and managed it appropriately. In India, around 12 million people suffer from glaucoma, and 1.5 million are blind due to it, so making ...
S. Senjam
semanticscholar   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Tick bite risk factors and prevention measures in an area with emerging Powassan virus disease

Public Health Challenges, 2023
Background In the United States (U.S.), Powassan virus is primarily transmitted to humans by the black‐legged tick (Ixodes scapularis). Rarely, infections can present as severe neuroinvasive disease.
Nicolette Wilson, Grace M. Vahey, Emily McDonald, Kelly Fitzpatrick, Jennifer Lehman, Sandhya Clark, Kristine Lindell, Daniel M. Pastula, Stephen Perez, Heather Rhodes, Carolyn V. Gould, J. Erin Staples, Stacey W. Martin, Kim Cervantes   +13 more
doaj   +1 more source

Malaria risk and receptivity: Continuing development of insecticide resistance in the major malaria vector Anopheles arabiensis in northern KwaZulu-Natal, South Africa

South African Journal of Science, 2022
Malaria incidence in South Africa is highest in the three endemic provinces: KwaZulu-Natal, Mpumalanga and Limpopo. The contribution to malaria transmission by several mosquito species, variation in their resting behaviours and low levels of insecticide
Givemore Munhenga, Shüné V. Oliver, Leanne N. Lobb, Theresa T. Mazarire, Windy Sekgele, Thabo Mashatola, Nondumiso Mabaso, Dumsani M. Dlamini, Malibongwe Zulu, Fortunate Moletsane, Blaženka D. Letinić, Jacek Zawada, Ashley Burke, Avhatakali Matamba, Basil D. Brooke   +14 more
doaj   +1 more source

Communicable diseases: a global perspective

, 2020
Completely updated and revised, and now published in its 6th edition, this book includes 20 chapters providing an essential overview of infectious diseases for almost 25 years. A comprehensive yet synoptic account of infectious diseases, it covers theory,

semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Free-living amoebae infections in humans in South Africa, 1996-2023

International Journal of Infectious Diseases
Introduction: Free-living amoebae (FLA) exist independently in various environments such as soil and water and do not rely on human or animal hosts for survival.
Dr Shareen Boughan, Mrs Bhavani Moodley, Prof John Frean, Dr Charlotte Sriruttan-Nel   +3 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production

Frontiers in Microbiology, 2020
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo, Patrick I. Mpingabo, Shuzo Urata, Shuzo Urata, Jiro Yasuda, Jiro Yasuda, Jiro Yasuda   +6 more
doaj   +1 more source