Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Recurrent nasopharyngeal rhinosporidiosis: Case report from Qatar and review of the literature
Rhinosporidiosis is a chronic granulomatous infectious disease that predominantly affects the mucosal membranes of the nose and nasopharynx. The disease is caused by Rhinosporidium seeberi, an eukaryotic pathogen with distinct geographical distribution ...
Gawahir M. Ali +5 more
doaj +1 more source
The prevalence, communicability and co-occurrence of inverted hallucinations: an overlooked global public health concern [PDF]
While scientific understanding concerning the role of biological pathogenic agents in the transmission of communicable diseases has increased markedly in recent decades, the possibility of a psychological pathogenic agent that underlies the transmission ...
Ducasse, Deborah +3 more
core +1 more source
Emerging challenges and health system capacity: the case of non- communicable diseases in Pakistan; a review [PDF]
Background: Pakistan is facing double burden of disease and the contribution of mortality by non-communicable diseases has over numbered the communicable diseases.
Malik, Muhammad Ashar, Zafar, Mubashir
core +2 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Candida glabrata chorioamnionitis following IVF pregnancy
Fungal chorioamnionitis is a rare but potentially life-threatening complication of pregnancy with significant maternal and fetal consequences. We describe a severe case of Candida glabrata chorioamnionitis in a 19-week twin pregnancy conceived through in
Junais Koleri +5 more
doaj +1 more source
Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one-third to two-thirds of the patients with SLE progress to lupus nephritis (LN). The pathogenesis of SLE and LN has not yet been fully elucidated, and effective treatment
Hui-Yuan Li +8 more
doaj +1 more source
Communicable diseases: provisional summary 2003. [PDF]
This report summarises the main trends in communicable disease in Northern Ireland during 2003. It is primarily based on laboratory reports forward to CDSC (NI) and information supplied by Consultants in Communicable Disease Control.
core
The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysis [PDF]
Maureen Moyo-Chilufya +5 more
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source

