Results 81 to 90 of about 9,757,173 (343)

Metabolomics: A Scoping Review of Its Role as a Tool for Disease Biomarker Discovery in Selected Non-Communicable Diseases

Metabolites, 2021
Metabolomics is a branch of ‘omics’ sciences that utilises a couple of analytical tools for the identification of small molecules (metabolites) in a given sample.
Adewale V. Aderemi, A. Ayeleso, O. Oyedapo, E. Mukwevho   +3 more
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Investigation of Salmonella Enteritidis outbreaks in South Africa using multi-locus variable-number tandem-repeats analysis, 2013-2015

BMC Infectious Diseases, 2017
Background Salmonella enterica serovar Enteritidis (Salmonella Enteritidis) has become a significant pathogen in South Africa, and the need for improved molecular surveillance of this pathogen has become important.
Munyadziwa Muvhali, Anthony Marius Smith, Andronica Moipone Rakgantso, Karen Helena Keddy   +3 more
doaj   +1 more source

Are Communicable Diseases Only Communicable?

, 2021
For half a century, the so-called epidemiological transition model has guided the interpretation of mortality data. Based on long-term trends in morbidity, it focuses on declining mortality from communicable diseases and the rise of non-communicable chronic diseases (primarily cancer and cardiovascular diseases).
Cavalin, Catherine, Rosental, Paul-André   +1 more
openaire   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study

BMC Infectious Diseases, 2020
Background There are limited data on Coronavirus Disease 2019 (COVID-19) outcomes at a national level, and none after 60 days of follow up. The aim of this study was to describe national, 60-day all-cause mortality associated with COVID-19, and to ...
Ali S. Omrani, Muna A. Almaslamani, Joanne Daghfal, Rand A. Alattar, Mohamed Elgara, Shahd H. Shaar, Tawheeda B. H. Ibrahim, Ahmed Zaqout, Dana Bakdach, Abdelrauof M. Akkari, Anas Baiou, Bassem Alhariri, Reem Elajez, Ahmed A. M. Husain, Mohamed N. Badawi, Fatma Ben Abid, Sulieman H. Abu Jarir, Shiema Abdalla, Anvar Kaleeckal, Kris Choda, Venkateswara R. Chinta, Mohamed A. Sherbash, Khalil Al-Ismail, Mohammed Abukhattab, Ali Ait Hssain, Peter V. Coyle, Roberto Bertollini, Michael P. Frenneaux, Abdullatif Alkhal, Hanan M. Al-Kuwari   +29 more
doaj   +1 more source

Obesity is a communicable disease

Journal of the Pakistan Medical Association
Obesity has multiple causes and correlates. Usually studied as a metabolic and endocrine disease, with mechanical and musculoskeletal comorbidities, obesity also has a communicable angle to it. Obesity can be considered a communicable disease from the conventional point of view, as it is associated with viral etiology in animal and human models.
Sanjay, Kalra, Madhur, Verma, Nitin, Kapoor   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Recurrent nasopharyngeal rhinosporidiosis: Case report from Qatar and review of the literature

IDCases, 2020
Rhinosporidiosis is a chronic granulomatous infectious disease that predominantly affects the mucosal membranes of the nose and nasopharynx. The disease is caused by Rhinosporidium seeberi, an eukaryotic pathogen with distinct geographical distribution ...
Gawahir M. Ali, Wael Goravey, Samir A. Al Hyassat, Mahir Petkar, Muna A. Al Maslamani, Hamad Abdel Hadi   +5 more
doaj   +1 more source