Results 41 to 50 of about 229,923 (267)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

PCC Voltage Compensation Scheme of MMC-MTDC System for Transient Stability Enhancement Under Communication Delay

IEEE Access, 2020
Multi-terminal High Voltage Direct Current (MTDC) with modular multilevel converter (MMC) is a promising technology, because it integrates diverse energy resources.
Xichang Wen, Jianchun Peng, Saddam Aziz, Hui Jiang   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Deep Reinforcement Learning Based Resource Allocation for Fault Detection with Cloud Edge Collaboration in Smart Grid

CSEE Journal of Power and Energy Systems
Real-time fault detection is important for operation of smart grid. It has become a trend of future development to design an anomaly detection system based on deep learning by using the powerful computing power of the cloud.
Qiyue Li, Yadong Zhu, Jinjin Ding, Weitao Li, Wei Sun, Lijian Ding   +5 more
doaj   +1 more source

Authority Transfer According to a Driver Intervention Intention Considering Coexistence of Communication Delay

Computers, 2023
Recently, interest and research on autonomous driving technology have been actively conducted. However, proving the safety of autonomous vehicles and commercializing autonomous vehicles remain key challenges.
Taeyoon Lim, Myeonghwan Hwang, Eugene Kim, Hyunrok Cha   +3 more
doaj   +1 more source

Scheduling on Grid with communication Delay

CoRR, 2015
Parallel processing, the core of High Performance Computing (HPC), was and still the most effective way in improving the speed of computer systems. For the past few years, the substantial developments in the computing power of processors and the network speed have strikingly changed the landscape of HPC.
openaire   +3 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Fixed-Time Event-Triggered Sliding Mode Consensus Control for Multi-AUV Formation Under External Disturbances and Communication Delays

Journal of Marine Science and Engineering
This paper addresses the consensus control challenge for multiple autonomous underwater vehicles’ (AUVs) formation operating under external disturbances and communication delays.
Kaihang Zhang, Wei Zhang, Xue Du, Zixuan Li   +3 more
doaj   +1 more source