Results 61 to 70 of about 118,371 (233)
Pharmacy, 2018 The Japanese pharmaceutical curriculum was extended from four to six years in 2006. Students now receive practical communication-skills training in their fourth year, before progressing to train in hospital and community pharmacies in their fifth year ...
Rie Kubota +7 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
At-Tarbawi, 2017 The research aims to report the improvement of the kindergarten students’ communication skill by implementing the chatting technique. This study is a collaborative action research.
Hery Setiyatna
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Zhongguo cuzhong zazhi目的 在神经科住院医师中开展困难谈话技能培训课程，探究困难谈话技能培训的可行性，并初步探索本课程的效果。 方法 在北京协和医院神经科住院医师中开展2次困难谈话技能培训课程，每月1次，每次2 h。课程主题均为与神经科临床实践相关的具体临床情景，包括：①告知坏消息；②与“困难”患者或家属沟通；③讨论不施行心肺复苏等抢救措施；④与家属讨论重症患者的临终关怀。采用情景模拟教学方法，邀请标准化病人和住院医师在教师指导下完成案例情景模拟，并进行医患沟通伦理知识、技能策略的学习 ...
尹翮翔，周立新，姚明，朱以诚，崔丽英，倪俊 (YIN Hexiang, ZHOU Lixin, YAO Ming, ZHU Yicheng, CUI Liying, NI Jun)
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Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Advances in Medical Education and Practice, 2021 Tesfamichael Alaro Agago,1 Shewatatek Gedamu Wonde,1 Senait Samuel Bramo,2 Tsedeke Asaminew1 1Health Sciences Institute, Jimma University, Jimma, Ethiopia; 2College of Natural Sciences, Jimma University, Jimma, EthiopiaCorrespondence: Tesfamichael Alaro ...
Agago TA, Wonde SG, Bramo SS, Asaminew T
doaj
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source