Results 61 to 70 of about 42,131 (268)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

PENILAIAN HASIL PEMBELAJARAN KEMAHIRAN BERBAHASA INDONESIA DENGAN PENDEKATAN KOMUNIKATIF

open access: yesCakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2010
: Assessment of the Indonesian Language Learning Outcomes Using the Communicative Approach. Since the 1994 Curriculum was launched up to now, the assessment of the Indonesian language learning outcomes has been directed to the student’s ability to use ...
Sumadi Sumadi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Didactics of physics in the Czech Republic: Trends, challenges and perspectives [PDF]

open access: yesPedagogická Orientace, 2011
The goal of this paper is to determinate the concept didactics of physics and topoint out the changes in the approaches to didactics of physics from both the applicativeand integrative approach to the communicative and information-communicativeapproach ...
Danuše Nezvalová
doaj  

The Use of Picture to Improve Students’ Speaking Skill in English

open access: yesIJET (Indonesian Journal of English Teaching), 2018
This study is aimed to investigate how to teach English speaking or conversation interestingly for students by using a picture so that the students are easier to learn and enjoy in speaking English to others in the classroom.
Rahmi Aulia Nurdini
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Pendekatan Pragmatik dalam Mendukung Kemampuan Komunikasi Lisan

open access: yesBuletin Al-Turas, 2013
Abstrak Tujuan dari komunikasi adalah untuk mendapatkan pesan dari orang lain secara jelas dan tidak ambigu. Melakukan komunikasi memerlukan usaha dari pengirim maupun penerima.
Saefudin Saefudin
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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