Results 71 to 80 of about 474,222 (313)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A simple start - A potential use of simplified english materials in the inclusive classroom [PDF]

open access: yes, 2003
This paper examines issues surrounding simplified English materials (SEMs) and their usage. It considers their value in light of widespread support for authentic materials, the communicative approach and bilingual support and learning, contrasting this ...
Rix, Jonathan
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Being in Common: In Celebration of Ronald W. Greene\u27s Woolbert Award [PDF]

open access: yes, 2015
Dr. Kristin Swenson\u27s contribution to Communication and Critical/Cultural Studies, Volume 12, Issue 4 ...
Swenson, Kristin A.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Discourse activity in the science classroom: a socio-cultural analytical and planning tool for teaching [PDF]

open access: yesInvestigações em Ensino de Ciências, 2002
In this paper an analytical tool, or framework, for charactersing the ways in which teachers interact with students to promote meaning making, on the social plane of high school science classes, is introduced. The development of the framework is based on
Eduardo Fleury Mortimer, Phil Scott
doaj  

Task-based Language Teaching and Text Types in Teaching Writing Using Communicative Approach

open access: yesSHS Web of Conferences, 2018
One of the most important language competencies in teaching learning process is writing. The present study focused on investigating the effect of communicative approach with task-based language teaching and communicative approach on the students’ writing
Riyana Sari Ni Nyoman   +2 more
doaj   +1 more source

The Use of Picture to Improve Students’ Speaking Skill in English

open access: yesIJET (Indonesian Journal of English Teaching), 2018
This study is aimed to investigate how to teach English speaking or conversation interestingly for students by using a picture so that the students are easier to learn and enjoy in speaking English to others in the classroom.
Rahmi Aulia Nurdini
doaj   +1 more source

Listening & Speaking, Reading & Writing: Improving Four English Language Skills through the Eclectic Approach of International Educators in Japan [PDF]

open access: yes, 2018
This paper elaborates on the language teaching experiences of four international educators working in Japan. With diverse nationalities and backgrounds, and as language learners themselves, these professionals’ eclectic approach is the result of many ...
Karsten, Angela Marli   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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