Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Mindreading in a dog: an adaptation of a primate ‘mental attribution’ study [PDF]
In the framework of a longitudinal case study on a male tervueren dog, Philip, the present paper was aimed to get a more sophisticated insight into the cognitive functioning of the dog's mind.
Erdőhegyi, Ágnes +3 more
core +1 more source
Pagans and Satan and Goths, Oh My: Dark Leisure as Communicative Agency and Communal Identity on the Fringes of the Modern Goth Scene [PDF]
Goth music's cultural terrain has been extensively mapped in the first decade of this century. Through a dark leisure framework, the present article examines the way in which parts of the Goth scene embraced paganism and, latterly, Satanism, as actual ...
Spracklen, B, Spracklen, K
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Discourse activity in the science classroom: a socio-cultural analytical and planning tool for teaching [PDF]
In this paper an analytical tool, or framework, for charactersing the ways in which teachers interact with students to promote meaning making, on the social plane of high school science classes, is introduced. The development of the framework is based on
Eduardo Fleury Mortimer, Phil Scott
doaj
Task-based Language Teaching and Text Types in Teaching Writing Using Communicative Approach
One of the most important language competencies in teaching learning process is writing. The present study focused on investigating the effect of communicative approach with task-based language teaching and communicative approach on the students’ writing
Riyana Sari Ni Nyoman +2 more
doaj +1 more source
THE CORRELATION BETWEEN COMMUNICATIVE APPROACH BY USING 5W+H QUESTION AND STUDENT’S ABILITY IN SPEAKING SKILL AT THE EIGHT GRADE OF SMPN 1 SEDONG [PDF]
Soleh Abdussalam CORRELATION BETWEEN COMMUNICATIVE APPROACH BY USING 5W+H QUESTION AND STUDENT’S ABILITY IN SPEAKING SKILL AT TE EIGHT GRADE OF SMPN 1 SEDONG Communicative approach is an effective method of teaching English because it can be practiced ...
SOLEH ABDUSSALAM,
core
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The Use of Picture to Improve Students’ Speaking Skill in English
This study is aimed to investigate how to teach English speaking or conversation interestingly for students by using a picture so that the students are easier to learn and enjoy in speaking English to others in the classroom.
Rahmi Aulia Nurdini
doaj +1 more source

