Results 31 to 40 of about 218,415 (311)

An Approach to Pneumonia in Immunocompetent Patients

McGill Journal of Medicine, 2021
Pneumonia is a leading cause of morbidity. Pneumonia is defined as a lung inflammation of infectious etiology. It can be subcategorized into Community Acquired Pneumonia, Hospital Acquired Pneumonia and Ventilator Acquired Pneumonia.
Spandana Veeravalli, Safiya Soullane
doaj   +1 more source

Possibilities of predicting of the non-severe community-acquired pneumonia outcomes in patients with type 2 diabetes mellitus or chronic heart failure

Zaporožskij Medicinskij Žurnal, 2014
Aim. Сommunity-acquired pneumonia is life-threatening disease with level of fatal events in hospitals within 12-36 %. In turn, presence of congestive heart failure or type 2 diabetes increases the risk of adverse outcomes in patients with community ...
O. S. Makharynska, N. I. Imanova, M. M. Lebedinskayа   +2 more
doaj   +1 more source

Interrelation between systemic inflammation markers, endothelial dysfunction and coronary heart disease clinical course after community-acquired pneumonia

Patologìâ, 2015
Extensive research has established that community acquired pneumonia has negative impact on clinical course on coronary heart disease (CHD), but the pathogenic mechanism was not understood. Aim. To study the pro-inflammatory biomarkers and endothelial
N. S. Mykhailovska , T. O. Kulynych
doaj   +1 more source

Community-acquired bacterial pneumonia in adults: An update

The Indian journal of medical research, 2020
Community-acquired pneumonia (CAP) is the prominent cause of mortality and morbidity with important clinical impact across the globe. India accounts for 23 per cent of global pneumonia burden with case fatality rates between 14 and 30 per cent, and ...
V. Eshwara, C. Mukhopadhyay, J. Rello
semanticscholar   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Community-acquired pneumonia in critically ill very old patients: a growing problem

European Respiratory Review, 2020
Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit.
C. Cillóniz, C. Dominedò, J. Pericàs, D. Rodríguez-Hurtado, A. Torres   +4 more
semanticscholar   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Effect of vaccination on morbidity and mortality from community-acquired pneumonia

Acta Biomedica Scientifica
Background. Community-acquired pneumonia remains one of the most common and life-threatening forms of pathology among respiratory diseases.The aim of the study. To identify the features of the epidemiology of communityacquired pneumonia in the conditions
T. A. Bayanova, E. S. Stukova, N. A. Kravchenko   +2 more
doaj   +1 more source