Results 51 to 60 of about 814,123 (319)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Making sense of assets: Community asset mapping and related approaches for cultivating capacities [PDF]

, 2016
This working paper critically reviews some main aspects from asset based approaches highlights key strengths and weaknesses for future research/development.
Alevizou, Giota, Alexiou, Katerina, Zamenopoulos, Theo   +2 more
core  

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Online classroom or community-in-the-making? Instructor conceptualizations and teaching presence in international online contexts [PDF]

, 2011
The community of inquiry framework (Garrison, Anderson, & Archer, 2000) has been an important contribution to the online distance education field and has been useful in providing researchers with the construct of "teaching presence". Teaching presence as

core  

Sport development and physical activity promotion : an integrated model to encourage collaboration and enhance understanding [PDF]

, 2012
As inactivity and obesity levels continue to rise, calls are being made for sport development action to be further directed towards capitalising on the value of community participation for health and social benefits.
Ajzen, Alexandris, Bauman, Bauman, Beaton, Beaton, Bloomfield, Bloyce, Casey, Casey, Cleland, Coles, Commonwealth of Australia, Commonwealth of Australia, David Shilbury, Eime, Elder, Erica Hinckson, Funk, Funk, Giles-Corti, Giles-Corti, Giles-Corti, Glanz, Green, Green, Hallal, Henderson, Henderson, Houlihan, Hoye, Humbert, Hylton, Hylton, Independent Sport Panel, Katie Rowe, Kohl, Lesley Ferkins, Lounsbury, Macniven, O’Connor, O’Connor, Prochaska, Prochaska, Robson, Sallis, Sallis, Sallis, Sallis, Shilbury, Shilbury, Shilbury, Standing Committee on Recreation and Sport, Stewart, Stokols, Stokols, Vail, Victorian Curriculum and Assessment Authority, World Health Organisation, World Health Organisation   +59 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Shared Metacognition in a Community of Inquiry

Online Learning, 2022
The article begins with a review of the shared metacognition construct and its function within the Community of Inquiry theoretical framework. The primary focus of the shared metacognition construct is the role of learners to take responsibility and ...
Randy Garrison
doaj   +1 more source

Trust, Well-being and the Community of Philosophical Inquiry [PDF]

, 2015
Trust is vital for individuals to flourish and have a sense of well-being in their community. A trusting society allows people to feel safe, communicate with each other and engage with those who are different to themselves without feeling fearful.
D'Olimpio, Laura
core   +1 more source