Results 41 to 50 of about 166,443,361 (248)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Using the Community of Inquiry Framework to Scaffold Online Tutoring

open access: yesInternational Review of Research in Open and Distributed Learning, 2017
Tutoring involves providing learners with a suitable level of structure and guidance to support their learning. This study reports on an exploration of how to design such structure and guidance (i.e., learning scaffolds) in the Chinese online educational
Xiaoying Feng, Jingjing Xie, Yue Liu
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Narrative Oriented Inquiry: A Dynamic Framework for Good Practice [PDF]

open access: yes, 2009
Recently, (see Hiles and Čermák, 2008), we have proposed a psychological approach to narrative research that we call Narrative Oriented Inquiry (NOI). The focus of this approach is upon research with personal narratives, especially data collected from ...
Hiles, David   +2 more
core   +4 more sources

A Comprehensive Community of Inquiry Framework for Exploring Technology Enhanced Language Learning

open access: yesIAFOR Journal of Education, 2022
The use of technology for second language (L2) acquisition has become ubiquitous, but little thought has been given to the factors that impact the language learning experience.
Irum Alvi
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Learner Presence Matters: A Learner-Centered Exploration into the Community of Inquiry Framework

open access: yesOnline Learning, 2021
In the present study we explored the Community of Inquiry (CoI) framework, a theoretical structure identifying processes leading to effective online learning, within one particular learning context.
Catherine A Honig, Diane Salmon
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating the Effect of Direct Instruction of Argument Mapping Strategies on Cognitive Presence among Participants in the Online Community of Inquiry [PDF]

open access: yes, 2016
The purpose of this study was to investigate the effect of direct instructions of argument mapping strategies on students’ perception of their cognitive presence in the online community of inquiry.
Teeba, Obaid
core  

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