Results 241 to 250 of about 428,182 (296)

Psychological symptoms, comorbidities and symptom items associated with self-reported mental health needs in college students. [PDF]

BMC Psychiatry
Liu Y, Yang P, Feng H, Li D, Li S, Xu S, Chen H.   +6 more
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Anaemia of inflammation and cancer risk according to comorbidity in patients aged 40-89 years: a Danish cohort study. [PDF]

BMC Cancer
Boennelykke A, Østgård LSG, Falborg AZ, Vedsted P.   +3 more
europepmc   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

Advanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Exploring the renal-cardiovascular axis regulation mechanism and nursing considerations for cardiovascular disease and chronic kidney disease comorbidities based on the 2013-2014 NHANES database. [PDF]

Medicine (Baltimore)
Li L, Zhang Y, Cheng F.
europepmc   +1 more source

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

Advanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao, Yaqin Huang, Jiazhong Shi, Xiaozhou Zhou, Johan Bourghardt Fagman, Liwei Wang, Sha Liu, Wuxing Wang, Yuting Liu, Zhiwen Chen, Jin Yang   +10 more
wiley   +1 more source

Trends in Bidirectional Screening and Treatment Outcomes for Tuberculosis/HIV Comorbidity - China, 2020-2024. [PDF]

China CDC Wkly
Zhang G, Meng Q, Qu T, Zhou L, Liu E.
europepmc   +1 more source

Influence of risk factors and comorbidities on the successful therapy and survival of patients with critical limb ischemia.

, 2013
Mihaela Ioana Constantinescu, Dan Constantinescu, Bogdan Augustin Chiş, A Andercou, Ion Aurel Mironiuc   +4 more
openalex   +1 more source

Key Comorbidities and Risk Factors Associated with Chronic Kidney Disease Prevalence and Prognosis in China: Perspectives Based on the Global Burden of Disease Database and Comparison with the World Statistics

LI Meng-jin, Lei Yuan, Xue Cheng, Xu Jing, Tian Shi-yin, Zhiguo Mao   +5 more
openalex   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source