Results 21 to 30 of about 159,384 (275)
Le numérique au service de la valorisation des compétences des jeunes adultes
Interfaces Numériques, 2022 Cette contribution questionne les modalités d’apprentissage des jeunes utilisateurs d’interfaces numériques. À la suite d'Auray (2016), nous analysons les aptitudes à maîtriser les environnements numériques, en discutant la typologie en 4 compétences qu ...
Marion COVILLE +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Et si les malentendus sociocognitifs faisaient ou défaisaient l’effet-maître ?
Questions Vives, 2012 This paper aims to take stock on the contributions and the limits of the “teacher-effects” researches, effects of processes – product type. It observes a real shift between the measurement tool (test) of the teaching efficiency and the expectation of ...
Sabine Kahn
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Prise en compte des évolutions de compétences pour les ressources humaines [PDF]
, 2011 Les impératifs croissants de réactivité des entreprises manufacturières face à l’instabilité des marchés suscite un fort besoin de flexibilité dans leur organisation.
Le Lann, Jean-Marc +2 more
core
, 2023 peer reviewedLe concept d’Assessment Literacy est très présent dans de nombreux travaux américains (voir DeLuca et al., 2016 pour une synthèse). Les enseignants qui disposent de bonnes connaissances et compétences évaluatives favoriseraient ainsi la ...
Baron, Jean, Fagnant, Annick
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Médiations & Médiatisations, 2022 Polytechnique Montréal s’est doté d’un portfolio numérique pour faire le suivi et l’évaluation des 12 compétences requises par le Bureau canadien d’agrément des programmes de génie.
Anastassis Kozanitis +2 more
doaj +1 more source