Results 81 to 90 of about 228,337 (250)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

open access: yesFEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo   +4 more
wiley   +1 more source

Global Strategic Benchmarking, Critical Capabilities and Performance of Aerospace Subcontractors [PDF]

open access: yes
The aerospace industry faces fierce and rapidly changing competition worldwide which exercises a considerable amount of strain on its manufacturing subcontractors.
Louis A. Lefebvre, Élisabeth Lefebvre
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

L’EVALUATION DES COMPETENCES DES MANAGERS DE PROXIMITE DE L’EDUCATION-FORMATION : UN CHANTIER POUR BATIR L’ECOLE DE LA QUALITE ET LA PERFORMANCE

open access: yesRevue Marocaine de Recherche en Management et Marketing, 2017
La vision stratégique de la réforme 2015-2030 réalisée par le Conseil Supérieur de l’Éducation, la Formation et la Recherche Scientifique(CSEFRS)intitulée«Pour une école de l’équité, de la qualité et de la promotion», est très ambitieuse ...
GUEDIRA MOHAMMED
doaj  

Évaluation de la mise en œuvre d’un dispositif de formation d’enseignants associés au Québec par le biais d’une recherche développement

open access: yesRevue Internationale de Pédagogie de l’Enseignement Supérieur, 2015
In order to synchronize the training of supervisors of student teachers in Quebec, videos and guidelines have been developed as educational devices.
Louise M. Bélair   +2 more
doaj   +1 more source

Knowledge economy, learning society and lifelong learning : a review of the French literature [PDF]

open access: yes
In this article, we propose the hypothesis that “the Learning society” is more a political slogan and prospect than a social reality (In France, as in most OECD countries, public investment in formal education and training has actually decreased since ...
Philippe Méhaut
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Predictors of massive haemoptysis after a first episode of mild-to-moderate haemoptysis in patients with cystic fibrosis

open access: yesERJ Open Research, 2020
Geoffrey Pavaut   +5 more
doaj   +1 more source

Les droits des victimes des crimes d’agression : est-ce une matière vague ou une notion simplement oubliée ? [PDF]

open access: yesMouvements et Enjeux Sociaux
Les droits des victimes des crimes d’agression révèlent une facette bien particulière de la réparation. Très souvent à travers des nombreuses études, on a souvent relevé la complexité des réparations dues aux victimes des crimes internationaux et on a ...
Josué Evariste SHABANI MUGUNDA
doaj  

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