Results 31 to 40 of about 568,668 (296)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Dual-Flow Structure to Design a Continuous and Compact Nature Reserve

IEEE Access, 2019
Establishing the conservation reserves is an efficient approach to protect various species, in which maintaining the spatial characteristics of the habit is an important issue.
Chih-Wei Lin, Wei-Hao Tu, Jin-Fu Liu
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Compact cinematics

NECSUS, 2016
In this essay we propose the term ‘compact cinematics’ for the study of the various compact, short, compressed, and miniature (audio)visual artifacts, forms, and practices that circulate in our everyday multimedia environment across technologies, genres, and disciplines.
Hesselberth, P., Poulaki, M.
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Overview of EXL-50 research progress

Nuclear Fusion
XuanLong-50 (EXL-50) is the first medium-size spherical torus (ST) in China, with the toroidal field of 0.5 T at a major radius of 50 cm. Central Solenoid (CS)—free and non-inductive current drive via electron cyclotron resonance heating (ECRH) were the ...
Yuejiang Shi, Yumin Wang, Bing Liu, Xianming Song, Shaodong Song, Xinchen Jiang, Dong Guo, Di Luo, Xiang Gu, Tiantian Sun, Xianli Huang, Zhi Li, Lili Dong, Xueyun Wang, Gang Yin, Mingyuan Wang, Wenjun Liu, Hanyue Zhao, Huasheng Xie, Liu Yong, Dongkai Qi, Bo Xing, Jiangbo Ding, Chao Wu, Lei Li, Haijun Zhang, Yuanming Yang, Xin Zhao, Enwu Yang, Wenwu Luo, Peihai Zhou, Lei Han, Qing Zhou, Hanqing Wang, Jiaqi Dong, Baoshan Yuan, Y.-K. Martin Peng, Minsheng Liu, the EXL-50 team   +38 more
doaj   +1 more source

Design of Ultracompact High‐Speed‐Integrated Lithium–Niobate Periodic Dielectric Waveguide Modulator

Advanced Photonics Research, 2022
Modern communications and microwave photonics require compact electro‐optic modulators with ultrahigh bandwidth and low power consumption. These requirements can be satisfied by integrated lithium–niobate electro‐optic modulators with high bandwidth and ...
Yifan Qi, Zheng Zhang, Wenhe Jia, Sai Chen, Yuanmu Yang, Yang Li   +5 more
doaj   +1 more source

Compact vortices [PDF]

The European Physical Journal C, 2017
We study a family of Maxwell-Higgs models, described by the inclusion of a function of the scalar field that represent generalized magnetic permeability. We search for vortex configurations which obey first-order differential equations that solve the equations of motion.
Bazeia, D., Losano, L., Marques, M.A., Menezes, R., Zafalan, I.   +4 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source