Results 91 to 100 of about 1,125,486 (341)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Shiyou jixie, 2021 At present, most of the current researches on bimetal-lined composite pipes do not consider the influence of the pipe end weld ring during the pipe making process, and the mechanical properties of the materials in the pipe making anticorrosion process ...
Chen Junwen +6 more
doaj
Journal of the London Mathematical SocietyAbstractWe demonstrate that the technology of Radin forcing can be used to transfer compactness properties at a weakly inaccessible but not strong limit cardinal to a strongly inaccessible cardinal. As an application, relative to the existence of large cardinals, we construct a model of set theory in which there is a strongly inaccessible cardinal ...
Tom Benhamou, Jing Zhang
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Topological approach to analyzing compactness and connectivity of settlement systems considering terrain constraints (case study of the Saratov Region) [PDF]
Известия Саратовского университета. Новая серия: Серия Науки о ЗемлеThe article examines the application of topological concepts for analysing the structure and assessing the compactness of a regional settlement system.
Danilov, Vladimir Anatolievich +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Controllability for fractional evolution inclusions without compactness
, 2015 In this paper, we study the existence and controllability for fractional evolution inclusions in Banach spaces. We use a new approach to obtain the existence of mild solutions and controllability results, avoiding hypotheses of compactness on the ...
Yong Zhou, V. Vijayakumar, R. Murugesu
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source