Results 81 to 90 of about 99,554 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Mapping Topsoil Behavior to Compaction at National Scale from an Analysis of Field Observations
LandSoil compaction is one of the most important and readily mitigated threats to soil health. Digital Soil Mapping (DSM) has emerged as an efficient method to provide broad-scale maps by combining soil information with environmental covariates.
Anne C. Richer-de-Forges +5 more
doaj +1 more source
Filomat, 2020 We introduce a new covering property, defined in terms of order types of sequences of open sets, rather than in terms of cardinalities. The most general form depends on two ordinal parameters. Ordinal compactness turns out to be a much more varied notion than cardinal compactness.
openaire +5 more sources
Measures of compactness in approach spaces [PDF]
, 1995 summary:We investigate whether in the setting of approach spaces there exist measures of relative compactness, (relative) sequential compactness and (relative) countable compactness in the same vein as Kuratowski's measure of compactness.
Baekeland, R., Lowen, R.
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A New Perspective On Soft Topology
Hittite Journal of Science and Engineering, 2018 In this paper, we approach the concept of soft topology with a different perspective. We define a soft topological space over given initial topological universe as a parameterization of subspaces of a topological space.
Mustafa Burç Kandemir
doaj +1 more source
, 1998 Compactness in Pavelka's fuzzy logic for some compact lattices of truth values is shown, and the concept of gradual compactness is introduced to establish some corresponding results in a more general ...
Ying, M
core +1 more source