Results 111 to 120 of about 38,779 (263)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimal bilinear control of nonlinear Hartree equation in R^3

open access: yesElectronic Journal of Differential Equations, 2013
This article concerns with the optimal bilinear control for the nonlinear Hartree equation in $mathbb{R}^3$, which describes the mean-field limit of many-body quantum systems.
Binhua Feng, Jiayin Liu, Jun Zheng
doaj  

Spatial Morphology Gene Map of Small Industrial and Mining Towns

open access: yesLand
The small towns influenced by the long-term impact of the industrial and mining industries have formed distinctive spatial morphology. A systematic exploration of their spatial form characteristics can make up for the deficiencies of the existing ...
Qiguo Li   +3 more
doaj   +1 more source

The Compactness Theorem

open access: yes, 2022
The compactness theorem is a fundamental theorem for the model theory of classical propositional and first-order logic. As well as having importance in several areas of mathematics, such as algebra and combinatorics, it also helps to pinpoint the ...
Leek, Robert; id_orcid, Paseau, A. C.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

COMPACTNESS OF TERRITORIAL HROMADAS OF VOLYN OBLAST IN THE CONTEXT OF SPATIAL PLANNING

open access: yesЕкономічна та соціальна географія
The purpose of the study is to analyze the spatial compactness of territorial hromadas in the Volyn oblast. Spatial compactness is an important geographical parameter of the functioning of territorial hromadas in the context of spatial planning.
Volodymyr LAZHNIK, Serhiy PUHACH
doaj   +1 more source

Sequential S?-compactness in L-topological spaces

open access: yes, 2017
In this paper, a new notion of sequential compactness is introduced in L-topological spaces, which is called sequentially S?-compactness. If L = [0, 1], sequential ultra-compactness, sequential N-compactness and sequential strong compactness imply ...
Li, Shu-Ping
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Compact High-Q Bandpass Filter Using 3-D Stacked Stripline

open access: yesMicromachines
This article presents a novel compact high-Q bandpass filter (BPF) utilizing a 3-D stacked stripline configuration. T-shaped stepped impedance resonators (SIRs) are employed to achieve miniaturization.
Yu Cao, Yong Liu, Junling He, Xin Xu
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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