Results 131 to 140 of about 38,779 (263)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Strongly nonlinear parabolic initial-boundary value problems in Orlicz spaces

open access: yesElectronic Journal of Differential Equations, 2002
problems. We also prove some compactness results in inhomogeneous Orlicz-Sobolev spaces.
Abdelhak Elmahi
doaj  

Sβ−COMPACTNESS IN L-TOPOLOGICAL SPACES ∗

open access: yes, 2005
In this paper, the notion of Sβ−compactness is introduced in Ltopological spaces by means of open βa−cover. It is a generalization of Lowen’s strong compactness, but it is different from Wang’s strong compactness. Ultra-compactness implies Sβ−compactness.
Antofagasta Chile, Fu Gui Shi
core  

Compact and weakly compact multiplications on C^∗-algebras

open access: yesAnnales Academiae Scientiarum Fennicae Series A I Mathematica, 1989
As proved by \textit{K. Vala} in [Ann. Acad. Sci. Fenn. Ser. A I 351, 9 p. (1964; Zbl 0132.098)], the linear operator \(X\mapsto SXT\), with \(S, T, X\) bounded operators on some Hilbert space \(H\), is compact on \(B(H)\) if and only if both S and T are compact operators (provided \(S\neq 0\) and \(T\neq 0)\).
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Directional oscillations, concentrations, and compensated compactness via microlocal compactness forms

open access: yes, 2014
This work introduces microlocal compactness forms (MCFs) as a new tool to study oscillations and concentrations in L p -bounded sequences of functions.
Filip Rindler, Rindler, Filip
core   +1 more source

Approximation and Compactness

open access: yesQuaestiones Mathematicae
Abstract: In approach theory convergence is described by means of limit and adherence operators acting on filters or ultrafilters. The value of the limit resp. adherence operator on an (ultra)filter in a point x is interpreted as the distance that the point x is away from being a limit resp. an adherence point of the (ultra)filter. A point were a limit
Colebunders, E., Lowen, R.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Compensation phenomena in geometric partial differential equations [PDF]

open access: yes
In this thesis we present optimal and improved estimates for systems of critical elliptic PDE which arise as generalisations of natural geometric problems.
Sharp, Benjamin G.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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