Results 131 to 140 of about 99,554 (305)
The compactness of countably compact spaces [PDF]
Pacific Journal of Mathematics, 1970 openaire +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Locally compact, $\omega_1$-compact spaces
, 2017 An $\omega_1$-compact space is a space in which every closed discrete subspace is countable. We give various general conditions under which a locally compact, $\omega_1$-compact space is $\sigma$-countably compact, i.e., the union of countably many countably compact spaces. These conditions involve very elementary properties.
Nyikos, Peter, Zdomskyy, Lyubomyr
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Yamabe boundary problem with scalar-flat manifolds target
Electronic Journal of Differential Equations, 2023 Marco G. Ghimenti, Anna Maria Micheletti
doaj
Electronic Journal of Differential Equations, 2012 In this article, we present results on the existence and the topological structure of the solution set for initial-value problems for the first-order impulsive differential equation $$displaylines{ (phi(y'))' = f(t,y(t)), quadhbox{a.e. } tin [0,b],cr
Johnny Henderson +2 more
doaj
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
The Open Limit Point Compactness
, 2014 In this paper, we gave a new topological concept and we called it the open limit point compactness.We have proved that each of the compactness, and the limit point compactness is stronger than of the open limit point compactness., that is, compactness ...
Hamza, AbedalHamza Mahdi
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source