Results 141 to 150 of about 38,779 (263)
Proyecciones (Antofagasta)We give a characterization in terms of the transpose operator for a continuous linear operator between locally convex spaces to map bounded sets into relatively weakly compact [relatively compact, precompact] sets. Our results give a known characterization for compact operators between Banach spaces.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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We explain how to think about and use the open cover definition of compactness through several examples. In particular, we argue that compactness should be thought of as a finiteness condition which is algorithmic in ...
Sun, Emory
core
The compactness of countably compact spaces [PDF]
Pacific Journal of Mathematics, 1970 openaire +3 more sources
Locally compact, $\omega_1$-compact spaces
, 2017 An $\omega_1$-compact space is a space in which every closed discrete subspace is countable. We give various general conditions under which a locally compact, $\omega_1$-compact space is $\sigma$-countably compact, i.e., the union of countably many countably compact spaces. These conditions involve very elementary properties.
Nyikos, Peter, Zdomskyy, Lyubomyr
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
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, 2008 In my opinion, compactness is the most important concept in mathematics. We \u27ll track it from the one-dimensional real line in calculus to infinite dimensional spaces of functions and surfaces and see what it can ...
Morgan, Frank
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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