Results 51 to 60 of about 4,159,971 (305)
Liver as the target organ: what we can do to help the patient
Медицинский совет, 2013 Liver diseases of various origin are a common cause of morbidity and mortality. The pathogenetic mechanism of hepatocyte damage consists in the destruction of the membrane structure in a certain way. It is recommended to use drugs exhibiting revitalizing
E. B. Grishchenko, M. I. Shchyokina
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Competition Among Companies: Coexistence and Extinction
, 2002 We study a spatially homogeneous model of a market where several agents or companies compete for a wealth resource. In analogy with ecological systems the simplest case of such models shows a kind of "competitive exclusion" principle.
Agrawal +20 more
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Virology Journal, 2017 Background Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group.
Joan E. M. van der Lubbe +7 more
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Assessing Financial Reporting Quality of Early Stage Private Companies [PDF]
, 2017 There are a variety of widely accepted methods that are used in order to evaluate the financial positioning of companies that are traded on stock exchanges.
Evans, Devereux D
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FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Designing the Business Model of Herbal Pharmaceutical Knowledge based Companies [PDF]
, 2017 Today, research has indicated Knowledge based companies as a potential area in promoting knowledge economy, and due to the substantial added-value they make in the knowledge economy of the countries, these companies play a pivotal role in producing ...
Akbari, Morteza +3 more
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
YESTERDAY AND TODAY THE CENTER OF LABORATORY REFERENCE MATERIALS LTD «ECOHIM»
Стандартные образцы, 2017 The article describes the experience of the development and production of certified reference materials intended for metrological maintenance of ecological and analytical measurement and control oil product quality.
V. O. Arapov +2 more
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