Results 31 to 40 of about 459,901 (268)
The acute adverse health effects of kratom: an evaluation of case reports
Frontiers in PharmacologyMitragyna speciosa, commonly known as kratom, has gained popularity in the United States due to its stimulant and analgesic effects. Allegations of kratom-associated adverse health effects, primarily based on case reports/series, have obtained media ...
Sarah Smallets +4 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
SLAS Discovery, 2023 Recent advances in automated microscopy and image analysis enables quantitative profiling of cellular phenotypes (Cell Painting). It paves the way for studying the broad effects of chemical perturbations on biological systems at large scale during lead ...
Alemu Takele Assefa +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
INFLAMMATORY MYOFIBROBLASTIC TUMOR OF THE BLADDER
Вестник урологии, 2018 Inflammatory myofibroblastic tumor (IMT) is a neoplasm of low malignant potential. We report a case of inflammatory myofibroblastic tumor of the urinary bladder in a 30-year-old female treated with TURB.
A. S. Popko +3 more
doaj +1 more source
, 2008 AbstractManagement by missions (MBM) starts by asking a fundamental question: What is your company for? It seems reasonable to assume that an organization and its members should have a clear idea of why they exist. In practice, however, that is not always the case.
Pablo Cardona, Carlos Rey
openaire +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Медицинский совет, 2013 The term chronic pancreatitis (CP) is used to denote a group of chronic diseases of the pancreas of various etiology, predominantly inflammatory, with several phases of progress, and characterized by focal, segmental or diffuse degenerative and ...
M. I. Shchyokina, M. S. Panchuk
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Liver as the target organ: what we can do to help the patient
Медицинский совет, 2013 Liver diseases of various origin are a common cause of morbidity and mortality. The pathogenetic mechanism of hepatocyte damage consists in the destruction of the membrane structure in a certain way. It is recommended to use drugs exhibiting revitalizing
E. B. Grishchenko, M. I. Shchyokina
doaj +1 more source