Results 51 to 60 of about 1,811,188 (293)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A study on the current status of the canine artificial insemination

Journal of Animal Reproduction and Biotechnology
Artificial insemination (AI) is a widely used assisted reproductive technology in livestock, but its commercialization in dogs remains limited. With the growing demand in the pet industry, it is necessary to evaluate the efficiency and commercial ...
Kangmin Park, Hyeyoung Jeong, Joohyeong Lee   +2 more
doaj   +1 more source

Effects of reduced kinematic and social play experience on affective appraisal of human-rat play in rats

Frontiers in Zoology, 2023
Background Play is a common and developmentally important behaviour in young mammals. Specifically in Norway rats (Rattus norvegicus), reduced opportunity to engage in rough-and-tumble (RT) play has been associated with impaired development in social ...
Quanxiao Liu, Tereza Ilčíková, Mariia Radchenko, Markéta Junková, Marek Špinka   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Prospective Estimation of the Prevalence of Thromboembolism in Dogs With Inflammatory Protein‐Losing Enteropathy

Journal of Veterinary Internal Medicine
Background Inflammatory protein‐losing enteropathy (iPLE) is thought to be associated with a hypercoagulable state and may predispose dogs to thromboembolism (TE). However, little information is available regarding the prevalence of TE in dogs with iPLE.
Nene Oishi, Hiroshi Ohta, Masahiro Tamura, Kiwamu Hanazono, Kenjiro Miyoshi, Nozomu Yokoyama, Genya Shinbo   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Congenital urethral sphincter mechanism incompetence: observational clinical findings and treatment outcomes—a small retrospective study in 19 bitches

Acta Veterinaria Scandinavica
Background This study aimed to report observational clinical findings and treatment outcomes in a population of bitches affected with congenital urethral sphincter mechanism incompetence (CUSMI).
Pierre Langer, Charles Porsmoguer, Géraldine Bolen, Annick Hamaide, Stéphanie Noël   +4 more
doaj   +1 more source

Medial humeral epicondylar lesions and discreet calcified structures in the canine elbow: radiographic description of 183 cases

Acta Veterinaria Scandinavica, 2020
Background In this 4-year prospective observational study, all elbows in a dysplasia screening program including 14,073 dogs were studied using radiographs in two projections.
Arne Magnus Rørvik, Cathrine Trangerud, Jorunn Grondalen   +2 more
doaj   +1 more source