Results 61 to 70 of about 305,261 (307)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Chrysin Induces Apoptosis and Autophagy in Human Melanoma Cells via the mTOR/S6K Pathway

Biomedicines, 2022
Chrysin is known to exert anti-inflammatory, antioxidant, and anticancer effects. The aim of this study was to investigate the anticancer effects of chrysin in the human melanoma cells A375SM and A375P.
Jae-Han Lee, Eun-Seon Yoo, So-Hee Han, Gi-Hwan Jung, Eun-Ji Han, Eun-Young Choi, Su-ji Jeon, Soo-Hyun Jung, BumSeok Kim, Sung-Dae Cho, Jeong-Seok Nam, Changsun Choi, Jeong-Hwan Che, Ji-Youn Jung   +13 more
doaj   +1 more source

Effects of reduced kinematic and social play experience on affective appraisal of human-rat play in rats

Frontiers in Zoology, 2023
Background Play is a common and developmentally important behaviour in young mammals. Specifically in Norway rats (Rattus norvegicus), reduced opportunity to engage in rough-and-tumble (RT) play has been associated with impaired development in social ...
Quanxiao Liu, Tereza Ilčíková, Mariia Radchenko, Markéta Junková, Marek Špinka   +4 more
doaj   +1 more source

The companion dog as a model for human aging and mortality [PDF]

, 2018
Around the world, human populations have experienced large increases in average lifespan over the last 150 years, and while individuals are living longer, they are spending more years of life with multiple chronic morbidities.
Agur, Alexander, Armitage, Bartlett, Bonnett, Cianciolo, de Bruin, DuGoff, Fall, Finkel, Flegal, Fleming, Fortin, Fran, Freeman, Friedmann, German, Greeley, Greeley, Head, Herndon, Hess, Hoffman, Hoffman, Jin, Kaeberlein, Kaeberlein, Kennedy, Kraus, Leroy, Marconato, Nijland, O'Neill, O'Neill, Ostrander, Ownby, R Core Team, Rera, Rowell, Simms, Snyder, Sturm, Sutter, Tsutsumi, Virues-Ortega, Walsh, Wirth, Wolff   +47 more
core   +3 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

A study on the current status of the canine artificial insemination

Journal of Animal Reproduction and Biotechnology
Artificial insemination (AI) is a widely used assisted reproductive technology in livestock, but its commercialization in dogs remains limited. With the growing demand in the pet industry, it is necessary to evaluate the efficiency and commercial ...
Kangmin Park, Hyeyoung Jeong, Joohyeong Lee   +2 more
doaj   +1 more source

Racing to retirement : understanding greyhounds' experiences of becoming pets : a dissertation presented in partial fulfilment of the requirements for the degree of Masters of Arts in Social Anthropology at Massey University, Manawatū, New Zealand [PDF]

, 2017
This thesis is a multispecies ethnographic investigation of the transition of retired racing greyhounds to domestic pets. The key aim of this research was to understand the greyhounds’ experiences of this transition.
Paap, Hannah
core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Prospective Estimation of the Prevalence of Thromboembolism in Dogs With Inflammatory Protein‐Losing Enteropathy

Journal of Veterinary Internal Medicine
Background Inflammatory protein‐losing enteropathy (iPLE) is thought to be associated with a hypercoagulable state and may predispose dogs to thromboembolism (TE). However, little information is available regarding the prevalence of TE in dogs with iPLE.
Nene Oishi, Hiroshi Ohta, Masahiro Tamura, Kiwamu Hanazono, Kenjiro Miyoshi, Nozomu Yokoyama, Genya Shinbo   +6 more
doaj   +1 more source

Companion animals and well-being in palliative care nursing: a literature review [PDF]

, 2015
Aims and objectives To evaluate and critique current knowledge regarding the role of animals in palliative care. To explore the impact that animals may have on the well-being of individuals and to identify gaps in the evidence base.
Barrett, David, MacDonald, Julie M.
core   +1 more source