Results 91 to 100 of about 286,740 (309)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Efficacy of orally administered sodium benzoate and sodium phenylbutyrate in dogs with congenital portosystemic shunts

Journal of Veterinary Internal Medicine, 2019
Background Hyperammonemia can result in hepatic encephalopathy, which in severe cases eventually can lead to coma and death. In dogs, congenital portosystemic shunts (CPSS) are the most common cause for hyperammonemia.
Giora van Straten, Diewke vanDalen, Sietske J. Mesu, Jan Rothuizen, Erik Teske, Bart Spee, Robert P. Favier, Ingeborg M. vanGeijlswijk   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Does having a pet influence the physical activity of their young female owners?

BMC Public Health, 2019
Background Many studies have shown that having a dog has an impact on the increase in physical activity (PA) of people. However, what is often not taken into account in many such studies is owning of other pets.
Kristýna Machová, Klára Daďová, Helena Chaloupková, Ivona Svobodová   +3 more
doaj   +1 more source

“I don’t want the responsibility:” The moral implications of avoiding dependency relations with companion animals [PDF]

, 2017
I argue that humans have moral relationships with dogs and cats that they could adopt, but do not. The obligations of those of us who refrain from incurring particular relationships with dogs and cats are correlative with the power of persons with what ...
Norlock, Kathryn J.
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Companion animal studies

Animal Welfare, 1995
This volume has been published from a workshop held by the Society for Companion Animal Studies (SCAS), which brought together researchers and potential researchers from differing technical backgrounds. It should be remembered that not all research is carried out in Universities or Research Institutes where experience and support exists for the ...
openaire   +2 more sources

Evidence in Practice – A Pilot Study Leveraging Companion Animal and Equine Health Data from Primary Care Veterinary Clinics in New Zealand [PDF]

, 2016
Veterinary practitioners have extensive knowledge of animal health from their day-to-day observations of clinical patients. There have been several recent initiatives to capture these data from electronic medical records for use in national surveillance ...
Amezcua, Buckland, Carroll, Chaudhry, Core Team R, Crump, Dórea, Henning, Jones, Kao, Kass, Kearsley-Fleet, Klompas, Lanyon, Li, Lund, Mateus, Mattin, Moore, Muellner, O’Neill, O’Neill, O’Neill, O’Neill, O’Neill, Pfeiffer, Radford, Reeder, Robertson, Robinson, Rogers, Sawford, Spackman, Summers, Sánchez-Vizcaíno, Venom Coding Group, Vourc’h, Wang, Ward, WHO, Wohlfender-Remy, Zurbrigg   +41 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs

Veterinary Sciences, 2019
Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually resulting
Xiaoyan Wu, Hsiaotzu Chien, Monique E. van Wolferen, Hedwig S. Kruitwagen, Loes A. Oosterhoff, Louis C. Penning   +5 more
doaj   +1 more source