Results 71 to 80 of about 62,869 (310)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A study of the transference between empathy towards companion animals and empathy towards humans in children [PDF]
, 2000 Plan AViolence in our society is a growing concern. There is evidence of increasing violent behavior in young children. Problems such as teasing and schoolyard bullying have turned into vicious attacks and even murder. Professionals and lay persons alike
Lind, Mary A.
core
The Role of Companion Dogs in the VA Maryland Health Care System Whole Health(y) GeroFit Program [PDF]
, 2023 GeroFit is a gym-based exercise program that promotes health and wellness among older sedentary veterans. The aims of the current study were to determine whether providing a companion dog as an alternative to gym-based exercise would similarly affect ...
Heidi K. Ortmeyer +3 more
core +1 more source
Frontiers in Veterinary ScienceIntroductionMicronutritional deficits are linked to increased morbidity and mortality. Canine atopic dermatitis (CAD) often presents with iron depletion and subclinical inflammation, despite their typical meat-based diets, suggesting widespread ...
Carolina Frizzo-Ramos +9 more
doaj +1 more source
A Novel Approach to Engaging Communities Through the Use of Human Behaviour Change Models to Improve Companion Animal Welfare and Reduce Relinquishment [PDF]
Experts consider tackling companion animal ownership problems, such as delayed veterinary treatment and a lack of appropriate care provision, to be key in striving towards improved animal welfare.
Natalie Powdrill-Wells +4 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Factors Affecting Canine Obesity Seem to Be Independent of the Economic Status of the Country—A Survey on Hungarian Companion Dogs [PDF]
, 2020 For a companion dog, the most important environmental factor is the owner, who is responsible for providing everything that is necessary for the health and welfare of the dog.
Torda Orsolya Julianna +3 more
core +1 more source
AnimalsCanine idiopathic pulmonary fibrosis (CIPF) is an interstitial lung disease reported in West Highland white terriers (WHWTs). B-mode ultrasonography (US) is used in human medicine as an adjunct tool for interstitial lung disease, including idiopathic ...
Eugénie Soliveres +5 more
doaj +1 more source