Results 191 to 200 of about 52,792 (267)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Identification and pathogen screening of ectoparasites from companion animals in urban Vientiane, Lao PDR. [PDF]

PLoS Negl Trop Dis
Phommadeechack V, Sungvornyothin S, Pan-Ngum W, Theppangna W, Phommasone K, Ashley EA, Chantratita N, Robinson MT, Potiwat R.   +8 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Uncovering antimicrobial resistance structures in <i>Staphylococcus</i> spp. from companion animals: latent class analysis of isolates from dogs. [PDF]

Front Vet Sci
Castro A, Ayzanoa B, Gutierrez V, Cuicapuza D, Zuñiga R, Ferradas C, Salvatierra G.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Oral drug delivery systems for companion animals: an integrative review of medicated treats, chewable tablets, and other pharmaceutical formulations. [PDF]

Braz J Vet Med
Dos Santos MG, Andrade JF, Feitosa VA.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Characterization of Antimicrobial Resistance and Potential Zoonotic Risk in Uropathogenic <i>Escherichia coli</i> Isolated from Companion Animals, with Genomic Analysis of Virulence Determinants in a Representative Isolate. [PDF]

Trop Med Infect Dis
DeZoysa AR, Kwan M, Edison LK, Barber R, Glick L, Denagamage T, Kariyawasam S.   +6 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Correction: Risk factors for, metrics of, and consequences of access to veterinary care for companion animals: A scoping review. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source