Results 61 to 70 of about 9,198,725 (312)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

MAQASHID SYARIAH INDEX DAN DEWAN KOMISARIS INDEPENDEN TERHADAP NILAI PERUSAHAN DENGAN PROFITABILITAS SEBAGAI VARIABEL MEDIASI PADA PERUSAHAAN ASURANSI SYARIAH

I-Finance, 2020
This study aims to examine the effect of maqashid syariah index, an independent board of commissioners on firm value by mediating profitability. The population in this study is sharia insurance companies listed on the Indonesia Stock Exchange.
Puji Sahara, Titin Hartini, Sri Delasmi Jayanti   +2 more
doaj   +1 more source

The value of the company and its fundamental strength

Procedia Computer Science, 2020
Abstract The basic goal of the company’s operation is to build its value. There are many measures, which makes value an ambiguous category. The value of the company is interested in its stakeholders, who can use the information about the value in various ways to achieve their goals, e.g. investing, managing the company, etc.
Waldemar Tarczynski, Malgorzata Tarczynska-Luniewska, Sebastian Majewski   +2 more
openaire   +2 more sources

Dividend Policy, Liquidity and Company Growth on Company Value in Pharmaceutical Companies

Indonesian Journal of Innovation Studies, 2023
This study aims to examine the effect of Dividend Policy, Liquidity, and Company Growth on Firm Value. The approach used in this research is a quantitative approach. The population in this study is pharmaceutical companies listed on the Indonesia Stock Exchange.
Ella Lukmawati, Misti Hariasih
openaire   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Effect of Corporate Governance Mechanisms on the Companies' Performance of Initial Public Offering in Tehran Stock Exchange [PDF]

مطالعات تجربی حسابداری مالی, 2016
Diffusion of corporate governance mechanisms leads to stabilize the financial markets, and economic growth and helps to companies to have a proper implementation of corporate governance in competition.
Ali Saghafi, Abdol Hossein Talebi Najafabadi   +1 more
doaj   +1 more source

Company Growth, Company Size, and Investment Decisions on Banking Company Value

Indonesian Journal of Innovation Studies, 2023
This study aims to examine the effect of firm growth, firm size, and investment decisions on firm value. The approach used in this research is a quantitative approach. The population in this study is banking companies listed on the Indonesia Stock Exchange. The sampling technique used purposive sampling method. The sample in this study was 72 companies
Lailatul Amelia, Detak Prapanca
openaire   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

The Impact of Obesity in the UAE: Real-world Physician and Patient Perspectives

Dubai Diabetes and Endocrinology Journal
Background: Limited evidence exists on the impacts of obesity in the United Arab Emirates (UAE). Real-world evidence is required to support obesity-related healthcare decision-making in the UAE.
Rita Nawar, Rahila Bhatti, Fatih Tangi, Soniya Rai, Tatjana Isailovic, Swarna Khare, Esther Artime, Victoria Higgins, Andrea Leith, Fatheya Al Awadi   +9 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source